诺唯赞:生物试剂行业领军者,未来成长可期
(以下内容从天风证券《诺唯赞:生物试剂行业领军者,未来成长可期》研报附件原文摘录)
Nanjing Vazyme Biotech (688105 CH) 生物试剂行业领军者,未来成长可期 Initiating coverage: biological reagent market leader with C19 and R&D growth prospects TP: RMB128.00 BUY (Initiation) 投资要点/Investment Thesis 投资要点/Investment Thesis 生物试剂行业进入发展期,进口替代方兴未艾 中国生命科学领域正在快速发展,科研经费的投入在增加,2019年基础生命科学研究、药物发现以及药物临床前研究投入的资金为866亿,2015-2019年复合增长率为18.8%,高于全球生命科学领域资金的增速。生命科学研究投入中10-15%用于生物试剂的投入,包括酶、抗原、抗体等原料。国内生物科研试剂领域起步较晚,正在进行进口替代。从产品类型上看,生物科研试剂分为分子类、蛋白类和细胞类,其中分子类占比50.9%最高。 Bio reagent industry enters development phase; import substitution takes hold China’s life sciences development recently received an influx of R&D funding, as investments to the tune of RMB86.6bn poured into the basic life sciences, new drug exploration and preclinical drug research areas. This represented a CAGR of 18.8% over 2015-19, faster than the global rate in life sciences. About 10-15% of this went into biological reagent research, including enzymes, antigens, antibodies and other raw materials. The country’s bio reagent R&D started later than others and we are seeing the import substitution trend take hold. The main categories are molecular, protein and cell reagent products, with molecular accounting for the highest proportion at 50.9%. 四大技术平台+酶库为核心竞争力,已初步形成下游客户黏性 公司深耕生命科学服务领域,经过近10年技术迭代建立围绕功能性蛋白质的关键共性技术平台和酶库——1)四大核心技术平台筑起研发壁垒,通过蛋白质定向改造与进化平台、单B细胞的高性能抗体发现平台、模化多系统重组蛋白制备平台和量子点修饰偶联与多指标联检技术平台,公司快速、高效、规模化地进行产品开发,现有200余种基因工程重组酶和1000余种高性能抗原和单克隆抗体等关键原料。2)酶库满足不同客户的需求,酶主要涉及高通量测序、等温扩增、PCR和qPCR等领域,覆盖上万种庞大的变体酶库。凭借着酶库和技术平台,公司客户覆盖1000多所科研院校、700多家高通量测序服务企业、700多家分子诊断试剂生产企业和200多家医药研发企业。 Competitive edge builds customer stickiness: 4 tech platforms and enzyme library The company’s life sciences solutions and services result from nearly 10 years of tech iteration. Its competitive barrier is formed by the establishment of key tech platforms and an enzyme library that are based on functional proteins: 1) Four core R&D tech platforms: through four high-performance platforms focused on cell-based antibody discovery, modular multi-system recombinant protein preparation, quantum dot modification coupling and multi-index joint inspection technology, the company is able to quickly develop products efficiently and to scale. Its collection comprises more than 200 kinds of genetically engineered recombinant enzymes and more than 1,000 kinds of high-performance antigens, monoclonal antibodies and other key raw materials. 2) Enzyme library: the company is able to fulfill the requirements of different customers due to its exhaustive enzyme library of tens of thousands of variants. The enzymes are used mainly in high-throughput sequencing, isothermal amplification, PCR and qPCR, and other fields. Vazyme’s enzyme library and technology platforms enable it to service customers from more than 1,000 scientific research institutions, more than 700 high-throughput sequencing service companies, more than 700 molecular diagnostic reagent manufacturers and more than 200 pharmaceutical R&D companies. 新冠抗原检测试剂盒国内获批,迎来第二增长曲线 2022年3月12日,公司新冠抗原检测试剂盒国内获批,可用于检测新型冠状病毒感染疑似人群,该抗原检测试剂可作为核酸检测的辅助和补充,配合国家新型冠状病毒检测策略,进一步提高“早发现”能力。截至2022年3月19日,国家药监局已批准17个新冠病毒抗原检测试剂产品。由于新冠疫情的反复以及毒株的变异,未来两年内新冠检测仍将需求较大,此次新型冠状病毒抗原检测试剂产品国内获批上市,进一步丰富了公司新型冠状病毒检测整体解决方案的应用场景,有助于提升公司在相关领域的竞争力。 Vazyme’s second growth driver: China-approved C19 antigen detection kits The Chinese authority approved Vazyme’s Covid-19 (C19) antigen detection kits on 12 March 2022, which test for C19 infection. The antigen detection reagent can be used as a supplement to aid nucleic acid tests. The product launch would be in line with China’s C19 testing strategy to enhance the country’s early detection capability. The State Food and Drug Administration approved 17 C19 antigen testing reagent products on 19 March 2022. With C19 pandemic resurgence and virus strain mutations, C19 tests would continue to be in demand for the next two years, in our view. Vazyme’s C19 antigen test reagent product is approved for medical listing in China, enriching application scenarios for its C19 testing solutions and raising its competitiveness. 投资建议/Investment Ideas 盈利预测与估值:我们预计 2021-2023 年公司收入分别为 18.64、24.40、26.68亿元,归母净利润分别为 6.78、8.80、9.78亿元。在生命科学业务领域标的中选取:泰坦科技、义翘神州、百普赛斯、阿拉丁四家标的作为可比公司,结合可比公司2022年平均PE为48倍,以及抗原检测获批将带来成长空间,因此给予公司一定估值溢价,2022年PE为58倍,对应目标价为128元人民币,首次覆盖,给予买入评级。 Profit forecast and risks: We expect Vazyme to generate revenue of RMB1.86bn/2.44bn/2.67bn in 2021/22/23E and net profit of RMB678m/880m/978m. Within the life sciences industry, we pick these four stocks to provide a peer comparison: Shanghai Titan Scientific, Sino Biological, Acrobiosystems and Aladdin Bio-Chem. Factoring in the 2022E average peer PE of 48x and growth potential increase from subsequent antigen test approvals, we accord a premium to Vazyme and assign a PE of 58x in 2022E. This derives our target price of RMB128 and hence initiate coverage with a BUY rating. 风险提示:新冠疫情不确定性风险、新冠抗体检测试剂盒的销量下降风险、竞争加剧风险、新品研发和推广不及预期风险、经营业绩增长不可持续和集中采购政策下新冠检测试剂中标单价下降风险。 Risks include: impact of C19 uncertainties; declining C19 antibody test kit sales; intensifying competition; below-expectation new product development and promotions; and falling C19 test reagent unit prices due to unsustainable business performance growth and the centralized procurement policy. Email: equity@tfisec.com TFI research report website: (pls scan the QR code) 本文件由天风国际证券集团有限公司, 天风国际证券与期货有限公司(证监会中央编号:BAV573)及天风国际资产管理有限公司(证监会中央编号:ASF056)(合称“天风国际集团”)编制,所载资料可能以若干假设为基础,仅供专业投资者作非商业用途及参考之用途,会因经济、市场及其他情况而随时更改而毋须另行通知。任何媒体、网站或个人未经授权不得转载、链接、转贴或以其他方式复制发表本文件及任何内容。已获授权者,在使用本文件或任何内容时必须注明稿件来源于天风国际集团,并承诺遵守相关法例及一切使用的国际惯例,不为任何非法目的或以任何非法方式使用本文件,违者将依法追究相关法律责任。本文件所引用之数据或资料可能得自第三方,天风国际集团将尽可能确认资料来源之可靠性,但天风国际集团并不对第三方所提供数据或资料之准确性负责。且天风国际集团不会就本文件所载任何资料、预测及/或意见的公平性、准确性、时限性、完整性或正确性,以及任何该等预测及/或意见所依据的基准作出任何明文或暗示的保证、陈述、担保或承诺而负责或承担任何法律责任。本文件中如有类似前瞻性陈述之内容,此等内容或陈述不得视为对任何将来表现之保证,且应注意实际情况或发展可能与该等陈述有重大落差。本文件并非及不应被视为邀约、招揽、邀请、建议买卖任何投资产品或投资决策之依据,亦不应被诠释为专业意见。阅览本文件的人士或在作出任何投资决策前,应完全了解其风险以及有关法律、赋税及会计的特点及后果,并根据个人的情况决定投资是否切合个人的投资目标,以及能否承担有关风险,必要时应寻求适当的专业意见。投资涉及风险。敬请投资者注意,证券及投资的价值可升亦可跌,过往的表现不一定可以预示日后的表现。在若干国家,传阅及分派本文件的方式可能受法律或规例所限制。获取本文件的人士须知悉及遵守该等限制。 阅读原文 立即开户
Nanjing Vazyme Biotech (688105 CH) 生物试剂行业领军者,未来成长可期 Initiating coverage: biological reagent market leader with C19 and R&D growth prospects TP: RMB128.00 BUY (Initiation) 投资要点/Investment Thesis 投资要点/Investment Thesis 生物试剂行业进入发展期,进口替代方兴未艾 中国生命科学领域正在快速发展,科研经费的投入在增加,2019年基础生命科学研究、药物发现以及药物临床前研究投入的资金为866亿,2015-2019年复合增长率为18.8%,高于全球生命科学领域资金的增速。生命科学研究投入中10-15%用于生物试剂的投入,包括酶、抗原、抗体等原料。国内生物科研试剂领域起步较晚,正在进行进口替代。从产品类型上看,生物科研试剂分为分子类、蛋白类和细胞类,其中分子类占比50.9%最高。 Bio reagent industry enters development phase; import substitution takes hold China’s life sciences development recently received an influx of R&D funding, as investments to the tune of RMB86.6bn poured into the basic life sciences, new drug exploration and preclinical drug research areas. This represented a CAGR of 18.8% over 2015-19, faster than the global rate in life sciences. About 10-15% of this went into biological reagent research, including enzymes, antigens, antibodies and other raw materials. The country’s bio reagent R&D started later than others and we are seeing the import substitution trend take hold. The main categories are molecular, protein and cell reagent products, with molecular accounting for the highest proportion at 50.9%. 四大技术平台+酶库为核心竞争力,已初步形成下游客户黏性 公司深耕生命科学服务领域,经过近10年技术迭代建立围绕功能性蛋白质的关键共性技术平台和酶库——1)四大核心技术平台筑起研发壁垒,通过蛋白质定向改造与进化平台、单B细胞的高性能抗体发现平台、模化多系统重组蛋白制备平台和量子点修饰偶联与多指标联检技术平台,公司快速、高效、规模化地进行产品开发,现有200余种基因工程重组酶和1000余种高性能抗原和单克隆抗体等关键原料。2)酶库满足不同客户的需求,酶主要涉及高通量测序、等温扩增、PCR和qPCR等领域,覆盖上万种庞大的变体酶库。凭借着酶库和技术平台,公司客户覆盖1000多所科研院校、700多家高通量测序服务企业、700多家分子诊断试剂生产企业和200多家医药研发企业。 Competitive edge builds customer stickiness: 4 tech platforms and enzyme library The company’s life sciences solutions and services result from nearly 10 years of tech iteration. Its competitive barrier is formed by the establishment of key tech platforms and an enzyme library that are based on functional proteins: 1) Four core R&D tech platforms: through four high-performance platforms focused on cell-based antibody discovery, modular multi-system recombinant protein preparation, quantum dot modification coupling and multi-index joint inspection technology, the company is able to quickly develop products efficiently and to scale. Its collection comprises more than 200 kinds of genetically engineered recombinant enzymes and more than 1,000 kinds of high-performance antigens, monoclonal antibodies and other key raw materials. 2) Enzyme library: the company is able to fulfill the requirements of different customers due to its exhaustive enzyme library of tens of thousands of variants. The enzymes are used mainly in high-throughput sequencing, isothermal amplification, PCR and qPCR, and other fields. Vazyme’s enzyme library and technology platforms enable it to service customers from more than 1,000 scientific research institutions, more than 700 high-throughput sequencing service companies, more than 700 molecular diagnostic reagent manufacturers and more than 200 pharmaceutical R&D companies. 新冠抗原检测试剂盒国内获批,迎来第二增长曲线 2022年3月12日,公司新冠抗原检测试剂盒国内获批,可用于检测新型冠状病毒感染疑似人群,该抗原检测试剂可作为核酸检测的辅助和补充,配合国家新型冠状病毒检测策略,进一步提高“早发现”能力。截至2022年3月19日,国家药监局已批准17个新冠病毒抗原检测试剂产品。由于新冠疫情的反复以及毒株的变异,未来两年内新冠检测仍将需求较大,此次新型冠状病毒抗原检测试剂产品国内获批上市,进一步丰富了公司新型冠状病毒检测整体解决方案的应用场景,有助于提升公司在相关领域的竞争力。 Vazyme’s second growth driver: China-approved C19 antigen detection kits The Chinese authority approved Vazyme’s Covid-19 (C19) antigen detection kits on 12 March 2022, which test for C19 infection. The antigen detection reagent can be used as a supplement to aid nucleic acid tests. The product launch would be in line with China’s C19 testing strategy to enhance the country’s early detection capability. The State Food and Drug Administration approved 17 C19 antigen testing reagent products on 19 March 2022. With C19 pandemic resurgence and virus strain mutations, C19 tests would continue to be in demand for the next two years, in our view. Vazyme’s C19 antigen test reagent product is approved for medical listing in China, enriching application scenarios for its C19 testing solutions and raising its competitiveness. 投资建议/Investment Ideas 盈利预测与估值:我们预计 2021-2023 年公司收入分别为 18.64、24.40、26.68亿元,归母净利润分别为 6.78、8.80、9.78亿元。在生命科学业务领域标的中选取:泰坦科技、义翘神州、百普赛斯、阿拉丁四家标的作为可比公司,结合可比公司2022年平均PE为48倍,以及抗原检测获批将带来成长空间,因此给予公司一定估值溢价,2022年PE为58倍,对应目标价为128元人民币,首次覆盖,给予买入评级。 Profit forecast and risks: We expect Vazyme to generate revenue of RMB1.86bn/2.44bn/2.67bn in 2021/22/23E and net profit of RMB678m/880m/978m. Within the life sciences industry, we pick these four stocks to provide a peer comparison: Shanghai Titan Scientific, Sino Biological, Acrobiosystems and Aladdin Bio-Chem. Factoring in the 2022E average peer PE of 48x and growth potential increase from subsequent antigen test approvals, we accord a premium to Vazyme and assign a PE of 58x in 2022E. This derives our target price of RMB128 and hence initiate coverage with a BUY rating. 风险提示:新冠疫情不确定性风险、新冠抗体检测试剂盒的销量下降风险、竞争加剧风险、新品研发和推广不及预期风险、经营业绩增长不可持续和集中采购政策下新冠检测试剂中标单价下降风险。 Risks include: impact of C19 uncertainties; declining C19 antibody test kit sales; intensifying competition; below-expectation new product development and promotions; and falling C19 test reagent unit prices due to unsustainable business performance growth and the centralized procurement policy. Email: equity@tfisec.com TFI research report website: (pls scan the QR code) 本文件由天风国际证券集团有限公司, 天风国际证券与期货有限公司(证监会中央编号:BAV573)及天风国际资产管理有限公司(证监会中央编号:ASF056)(合称“天风国际集团”)编制,所载资料可能以若干假设为基础,仅供专业投资者作非商业用途及参考之用途,会因经济、市场及其他情况而随时更改而毋须另行通知。任何媒体、网站或个人未经授权不得转载、链接、转贴或以其他方式复制发表本文件及任何内容。已获授权者,在使用本文件或任何内容时必须注明稿件来源于天风国际集团,并承诺遵守相关法例及一切使用的国际惯例,不为任何非法目的或以任何非法方式使用本文件,违者将依法追究相关法律责任。本文件所引用之数据或资料可能得自第三方,天风国际集团将尽可能确认资料来源之可靠性,但天风国际集团并不对第三方所提供数据或资料之准确性负责。且天风国际集团不会就本文件所载任何资料、预测及/或意见的公平性、准确性、时限性、完整性或正确性,以及任何该等预测及/或意见所依据的基准作出任何明文或暗示的保证、陈述、担保或承诺而负责或承担任何法律责任。本文件中如有类似前瞻性陈述之内容,此等内容或陈述不得视为对任何将来表现之保证,且应注意实际情况或发展可能与该等陈述有重大落差。本文件并非及不应被视为邀约、招揽、邀请、建议买卖任何投资产品或投资决策之依据,亦不应被诠释为专业意见。阅览本文件的人士或在作出任何投资决策前,应完全了解其风险以及有关法律、赋税及会计的特点及后果,并根据个人的情况决定投资是否切合个人的投资目标,以及能否承担有关风险,必要时应寻求适当的专业意见。投资涉及风险。敬请投资者注意,证券及投资的价值可升亦可跌,过往的表现不一定可以预示日后的表现。在若干国家,传阅及分派本文件的方式可能受法律或规例所限制。获取本文件的人士须知悉及遵守该等限制。 阅读原文 立即开户
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